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» Technologies for Integrating Biological Data
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BMCBI
2005
124views more  BMCBI 2005»
15 years 6 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
155
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RECOMB
2008
Springer
16 years 6 months ago
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
Next Generation Sequencing (NGS) technologies are capable of reading millions of short DNA sequences both quickly and cheaply. While these technologies are already being used for r...
Paul Medvedev, Michael Brudno
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
BIRTHDAY
2005
Springer
15 years 11 months ago
Toward Automated Large-Scale Information Integration and Discovery
The high cost of data consolidation is the key market inhibitor to the adoption of traditional information integration and data warehousing solutions. In this paper, we outline a n...
Paul Brown, Peter J. Haas, Jussi Myllymaki, Hamid ...
EMO
2005
Springer
108views Optimization» more  EMO 2005»
15 years 11 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...