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BMCBI
2010
96views more  BMCBI 2010»
13 years 10 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BMCBI
2006
155views more  BMCBI 2006»
13 years 10 months ago
AffyMiner: mining differentially expressed genes and biological knowledge in GeneChip microarray data
Background: DNA microarrays are a powerful tool for monitoring the expression of tens of thousands of genes simultaneously. With the advance of microarray technology, the challeng...
Guoqing Lu, The V. Nguyen, Yuannan Xia, Michael Fr...
EDBT
2009
ACM
241views Database» more  EDBT 2009»
14 years 4 months ago
GADDI: distance index based subgraph matching in biological networks
Currently, a huge amount of biological data can be naturally represented by graphs, e.g., protein interaction networks, gene regulatory networks, etc. The need for indexing large ...
Shijie Zhang, Shirong Li, Jiong Yang
IPPS
2009
IEEE
14 years 4 months ago
High-throughput protein structure determination using grid computing
Determining the X-ray crystallographic structures of proteins using the technique of molecular replacement (MR) can be a time and labor-intensive trial-and-error process, involvin...
Jason W. Schmidberger, Blair Bethwaite, Colin Enti...
IWOCA
2009
Springer
149views Algorithms» more  IWOCA 2009»
14 years 4 months ago
Randomized Postoptimization of Covering Arrays
The construction of covering arrays with the fewest rows remains a challenging problem. Most computational and recursive constructions result in extensive repetition of coverage. W...
Peyman Nayeri, Charles J. Colbourn, Goran Konjevod