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BMCBI
2007
94views more  BMCBI 2007»
13 years 8 months ago
A Hidden Markov Model to estimate population mixture and allelic copy-numbers in cancers using Affymetrix SNP arrays
Background: Affymetrix SNP arrays can interrogate thousands of SNPs at the same time. This allows us to look at the genomic content of cancer cells and to investigate the underlyi...
Philippe Lamy, Claus L. Andersen, Lars Dyrskjot, N...
BMCBI
2008
177views more  BMCBI 2008»
13 years 8 months ago
Baseline Correction for NMR Spectroscopic Metabolomics Data Analysis
Background: We propose a statistically principled baseline correction method, derived from a parametric smoothing model. It uses a score function to describe the key features of b...
Yuanxin Xi, David M. Rocke
CORR
2010
Springer
162views Education» more  CORR 2010»
13 years 8 months ago
Random sampling of lattice paths with constraints, via transportation
We investigate Monte Carlo Markov Chain (MCMC) procedures for the random sampling of some one-dimensional lattice paths with constraints, for various constraints. We will see that...
Lucas Gerin
COCO
2009
Springer
117views Algorithms» more  COCO 2009»
14 years 3 months ago
The Proof Complexity of Polynomial Identities
Devising an efficient deterministic – or even a nondeterministic sub-exponential time – algorithm for testing polynomial identities is a fundamental problem in algebraic comp...
Pavel Hrubes, Iddo Tzameret
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey