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BMCBI
2010
13 years 7 months ago
2010
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
BMCBI
2010
13 years 7 months ago
2010
Background: Prediction of catalytic residues is a major step in characterizing the function of enzymes. In its simpler formulation, the problem can be cast into a binary classific...
BMCBI
2007
13 years 7 months ago
2007
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
BMCBI
2007
13 years 7 months ago
2007
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
BMCBI
2007
13 years 7 months ago
2007
Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...