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GECCO
2003
Springer
113views Optimization» more  GECCO 2003»
14 years 26 days ago
Predicate Expression Cost Functions to Guide Evolutionary Search for Test Data
Several researchers are using evolutionary search methods to search for test data with which to test a program. The fitness or cost function depends on the test goal but almost in...
Leonardo Bottaci
BMCBI
2006
148views more  BMCBI 2006»
13 years 7 months ago
Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
Veronica Vinciotti, Xiaohui Liu, Rolf Turk, Emile ...
BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
JCB
2000
103views more  JCB 2000»
13 years 7 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
BMCBI
2007
147views more  BMCBI 2007»
13 years 7 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn