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ICGA
1997
122views Optimization» more  ICGA 1997»
13 years 9 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
AI
2008
Springer
13 years 8 months ago
What makes propositional abduction tractable
Abduction is a fundamental form of nonmonotonic reasoning that aims at finding explanations for observed manifestations. This process underlies many applications, from car configu...
Gustav Nordh, Bruno Zanuttini
BMCBI
2010
161views more  BMCBI 2010»
13 years 8 months ago
CGHpower: exploring sample size calculations for chromosomal copy number experiments
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...
BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2007
87views more  BMCBI 2007»
13 years 8 months ago
'Unite and conquer': enhanced prediction of protein subcellular localization by integrating multiple specialized tools
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
Yao Qing Shen, Gertraud Burger
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