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    BMCBI
    2007
    157views more  BMCBI 2007»
    Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
    13 years 8 months ago
    Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
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    Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
    Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
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    BMCBI
    2007
    157views more  BMCBI 2007»
    A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
    13 years 8 months ago
    A hybrid multiscale Monte Carlo algorithm (HyMSMC) to cope with disparity in time scales and species populations in intracellula
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    Background: The fundamental role that intrinsic stochasticity plays in cellular functions has been shown via numerous computational and experimental studies. In the face of such e...
    Asawari Samant, Babatunde A. Ogunnaike, Dionisios ...
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    BMCBI
    2010
    88views more  BMCBI 2010»
    Proteome scanning to predict PDZ domain interactions using support vector machines
    13 years 8 months ago
    Proteome scanning to predict PDZ domain interactions using support vector machines
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    Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
    Shirley Hui, Gary D. Bader
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    BMCBI
    2010
    102views more  BMCBI 2010»
    Peptide binding predictions for HLA DR, DP and DQ molecules
    13 years 8 months ago
    Peptide binding predictions for HLA DR, DP and DQ molecules
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    Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
    Peng Wang, John Sidney, Yohan Kim, Alessandro Sett...
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    BMCBI
    2008
    105views more  BMCBI 2008»
    A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
    13 years 8 months ago
    A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
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    Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
    Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
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