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BMCBI
2010
138views more  BMCBI 2010»
13 years 8 months ago
Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
Gayathri Jayaraman, Rahul Siddharthan
BMCBI
2010
182views more  BMCBI 2010»
13 years 8 months ago
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...
Jo A. Helmuth, Grégory Paul, Ivo F. Sbalzar...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
SODa: An Mn/Fe superoxide dismutase prediction and design server
Background: Superoxide dismutases (SODs) are ubiquitous metalloenzymes that play an important role in the defense of aerobic organisms against oxidative stress, by converting reac...
Jean Marc Kwasigroch, René Wintjens, Dimitr...
BMCBI
2007
118views more  BMCBI 2007»
13 years 8 months ago
A topological algorithm for identification of structural domains of proteins
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...
Frank Emmert-Streib, Arcady R. Mushegian
BMCBI
2010
105views more  BMCBI 2010»
13 years 8 months ago
Predicting phenotypic traits of prokaryotes from protein domain frequencies
Background: Establishing the relationship between an organism's genome sequence and its phenotype is a fundamental challenge that remains largely unsolved. Accurately predict...
Thomas Lingner, Stefanie Mühlhausen, Toni Gab...
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