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TCSB
2008
13 years 10 months ago
Clustering Time-Series Gene Expression Data with Unequal Time Intervals
Clustering gene expression data given in terms of time-series is a challenging problem that imposes its own particular constraints, namely exchanging two or more time points is not...
Luis Rueda, Ataul Bari, Alioune Ngom
BMCBI
2011
13 years 6 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
RECOMB
2009
Springer
14 years 11 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
CSB
2004
IEEE
152views Bioinformatics» more  CSB 2004»
14 years 2 months ago
Comparative Analysis of Gene Sets in the Gene Ontology Space under the Multiple Hypothesis Testing Framework
The Gene Ontology (GO) resource can be used as a powerful tool to uncover the properties shared among, and specific to, a list of genes produced by high-throughput functional geno...
Sheng Zhong, Lu Tian, Cheng Li, Kai-Florian Storch...
ICASSP
2011
IEEE
13 years 2 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero