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BMCBI
2007
141views more  BMCBI 2007»
13 years 10 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
BMCBI
2007
215views more  BMCBI 2007»
13 years 10 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
ISCI
2008
165views more  ISCI 2008»
13 years 10 months ago
Support vector regression from simulation data and few experimental samples
This paper considers nonlinear modeling based on a limited amount of experimental data and a simulator built from prior knowledge. The problem of how to best incorporate the data ...
Gérard Bloch, Fabien Lauer, Guillaume Colin...
JUCS
2008
186views more  JUCS 2008»
13 years 10 months ago
A Safe Dynamic Adaptation Framework for Aspect-Oriented Software Development
: One focus of current software development is the re-use of components in the construction of systems. Software Adaptation facilitates the consequent need to adapt these component...
Miguel Ángel Pérez Toledano, Amparo ...
KES
2008
Springer
13 years 10 months ago
Downsizing Multigenic Predictors of the Response to Preoperative Chemotherapy in Breast Cancer
We present a method for designing efficient multigenic predictors with few probes and its application to the prediction of the response to preoperative chemotherapy in breast cance...
René Natowicz, Roberto Incitti, Roman Rouzi...