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BMCBI
2007
141views more  BMCBI 2007»
15 years 2 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...
BMCBI
2007
215views more  BMCBI 2007»
15 years 2 months ago
Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregres
Background: Causal networks based on the vector autoregressive (VAR) process are a promising statistical tool for modeling regulatory interactions in a cell. However, learning the...
Rainer Opgen-Rhein, Korbinian Strimmer
ISCI
2008
165views more  ISCI 2008»
15 years 2 months ago
Support vector regression from simulation data and few experimental samples
This paper considers nonlinear modeling based on a limited amount of experimental data and a simulator built from prior knowledge. The problem of how to best incorporate the data ...
Gérard Bloch, Fabien Lauer, Guillaume Colin...
JUCS
2008
186views more  JUCS 2008»
15 years 2 months ago
A Safe Dynamic Adaptation Framework for Aspect-Oriented Software Development
: One focus of current software development is the re-use of components in the construction of systems. Software Adaptation facilitates the consequent need to adapt these component...
Miguel Ángel Pérez Toledano, Amparo ...
KES
2008
Springer
15 years 2 months ago
Downsizing Multigenic Predictors of the Response to Preoperative Chemotherapy in Breast Cancer
We present a method for designing efficient multigenic predictors with few probes and its application to the prediction of the response to preoperative chemotherapy in breast cance...
René Natowicz, Roberto Incitti, Roman Rouzi...