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» The ASTRAL compendium for protein structure and sequence ana...
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BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2007
150views more  BMCBI 2007»
13 years 7 months ago
Refining intra-protein contact prediction by graph analysis
Background: Accurate prediction of intra-protein residue contacts from sequence information will allow the prediction of protein structures. Basic predictions of such specific con...
Milana Frenkel-Morgenstern, Rachel Magid, Eran Eya...
BMCBI
2010
150views more  BMCBI 2010»
13 years 7 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
CANDC
2004
ACM
13 years 7 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
14 years 1 months ago
TPR Packing Analysis and 3D Modeling for the HAT Domain of Human Crooked Neck Protein
Human crooked neck protein (hcrn) containing 17 HAT or TPR repeats plays a role in pre-mRNA processing. Conserved residues in the TPR consensus sequence of 34 aa were found at hel...
Zhenglin Hou, Cunxi Wang, Odd-Arne Olsen