Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Gene prediction is one of the most challenging tasks in genome analysis, for which many tools have been developed and are still evolving. In this paper, we present a novel gene pr...
Rong She, Jeffrey Shih-Chieh Chu, Ke Wang, Nanshen...
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Aligning multiple DNA or protein sequences is a fundamental step in the analyses of phylogeny, homology and molecular structure. Heuristic algorithms are applied because optimal mu...