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    BMCBI
    2010
    95views more  BMCBI 2010»
    Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
    13 years 8 months ago
    Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
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    Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
    Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
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    BMCBI
    2008
    109views more  BMCBI 2008»
    ConStruct: Improved construction of RNA consensus structures
    13 years 8 months ago
    ConStruct: Improved construction of RNA consensus structures
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    Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
    Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
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    BMCBI
    2008
    78views more  BMCBI 2008»
    A new protein linear motif benchmark for multiple sequence alignment software
    13 years 8 months ago
    A new protein linear motif benchmark for multiple sequence alignment software
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    Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
    Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
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    BMCBI
    2008
    152views more  BMCBI 2008»
    Predicting biological system objectives de novo from internal state measurements
    13 years 8 months ago
    Predicting biological system objectives de novo from internal state measurements
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    Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
    Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
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    BMCBI
    2007
    162views more  BMCBI 2007»
    Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
    13 years 8 months ago
    Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
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    Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
    Namshin Kim, Christopher Lee
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