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» The Construction of Minimal DNA Expressions
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BMCBI
2005
116views more  BMCBI 2005»
13 years 9 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
BIOCOMP
2006
13 years 11 months ago
Data Mining of ESTs for Genetic Improvement of Salt Tolerance in Wheat
A total of 4,131 expressed sequence tags (ESTs) were selected from wheat EST database (http://wheat.pw.usda.gov/cgi-bin/westsql/est_lib.cgi.) to identify genic regions differing a...
Meral Unal, Ismail Cakmak, Yildiz Aydin, Aysen Yum...
BMCBI
2006
82views more  BMCBI 2006»
13 years 10 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco
BMCBI
2007
197views more  BMCBI 2007»
13 years 10 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park