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BMCBI
2006
135views more  BMCBI 2006»
13 years 9 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
BMCBI
2006
92views more  BMCBI 2006»
13 years 9 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2006
183views more  BMCBI 2006»
13 years 9 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
BMCBI
2006
143views more  BMCBI 2006»
13 years 9 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2006
154views more  BMCBI 2006»
13 years 9 months ago
An improved procedure for gene selection from microarray experiments using false discovery rate criterion
Background: A large number of genes usually show differential expressions in a microarray experiment with two types of tissues, and the p-values of a proper statistical test are o...
James J. Yang, Mark C. K. Yang
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