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» The Equivalence between Biology and Computation
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BMCBI
2008
89views more  BMCBI 2008»
13 years 10 months ago
Increasing the efficiency of bacterial transcription simulations: When to exclude the genome without loss of accuracy
Background: Simulating the major molecular events inside an Escherichia coli cell can lead to a very large number of reactions that compose its overall behaviour. Not only should ...
Marco A. J. Iafolla, Guang Qiang Dong, David R. Mc...
BMCBI
2007
99views more  BMCBI 2007»
13 years 10 months ago
Stratification bias in low signal microarray studies
Background: When analysing microarray and other small sample size biological datasets, care is needed to avoid various biases. We analyse a form of bias, stratification bias, that...
Brian J. Parker, Simon Günter, Justin Bedo
BMCBI
2008
142views more  BMCBI 2008»
13 years 10 months ago
Optimal neighborhood indexing for protein similarity search
Background: Similarity inference, one of the main bioinformatics tasks, has to face an exponential growth of the biological data. A classical approach used to cope with this data ...
Pierre Peterlongo, Laurent Noé, Dominique L...
CORR
2008
Springer
156views Education» more  CORR 2008»
13 years 10 months ago
Artificial Immune Systems (AIS) - A New Paradigm for Heuristic Decision Making
Over the last few years, more and more heuristic decision making techniques have been inspired by nature, e.g. evolutionary algorithms, ant colony optimisation and simulated annea...
Uwe Aickelin
BMCBI
2006
102views more  BMCBI 2006»
13 years 9 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik