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BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
BMCBI
2010
139views more  BMCBI 2010»
13 years 7 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
265views more  BMCBI 2007»
13 years 7 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
CORR
2008
Springer
139views Education» more  CORR 2008»
13 years 7 months ago
Exact two-terminal reliability of some directed networks
Abstract-- The calculation of network reliability in a probabilistic context has long been an issue of practical and academic importance. Conventional approaches (determination of ...
Christian Tanguy
BMCBI
2006
157views more  BMCBI 2006»
13 years 7 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik