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GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
14 years 2 months ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
BMCBI
2010
150views more  BMCBI 2010»
13 years 8 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
BIB
2008
109views more  BIB 2008»
13 years 8 months ago
Computational intelligence approaches for pattern discovery in biological systems
Biology, chemistry and medicine are faced by tremendous challenges caused by an overwhelming amount of data and the need for rapid interpretation. Computational intelligence (CI) ...
Gary B. Fogel
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 9 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
GECCO
2008
Springer
179views Optimization» more  GECCO 2008»
13 years 9 months ago
Evolution of discrete gene regulatory models
Gene regulatory networks (GRNs) are complex control systems that govern the interaction of genes, which ultimately control cellular processes at the protein level. GRNs can be ted...
Afshin Esmaeili, Christian Jacob