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KDD
2007
ACM
197views Data Mining» more  KDD 2007»
14 years 8 months ago
Learning the kernel matrix in discriminant analysis via quadratically constrained quadratic programming
The kernel function plays a central role in kernel methods. In this paper, we consider the automated learning of the kernel matrix over a convex combination of pre-specified kerne...
Jieping Ye, Shuiwang Ji, Jianhui Chen
KDD
2006
ACM
153views Data Mining» more  KDD 2006»
14 years 8 months ago
Spatial scan statistics: approximations and performance study
Spatial scan statistics are used to determine hotspots in spatial data, and are widely used in epidemiology and biosurveillance. In recent years, there has been much effort invest...
Deepak Agarwal, Andrew McGregor, Jeff M. Phillips,...
CHI
2004
ACM
14 years 8 months ago
Effects of instant messaging on the management of multiple project trajectories
We present a study of the effects of instant messaging (IM) on individuals' management of work across multiple collaborative projects. Groups of four participants completed f...
Susan R. Fussell, Sara B. Kiesler, Leslie D. Setlo...
RECOMB
2008
Springer
14 years 8 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
RECOMB
2006
Springer
14 years 8 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
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