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BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
INTEGRATION
2006
82views more  INTEGRATION 2006»
13 years 7 months ago
On whitespace and stability in physical synthesis
In the context of physical synthesis, large-scale standard-cell placement algorithms must facilitate incremental changes to layout, both local and global. In particular, flexible ...
Saurabh N. Adya, Igor L. Markov, Paul G. Villarrub...
TCAD
2008
99views more  TCAD 2008»
13 years 7 months ago
MP-Trees: A Packing-Based Macro Placement Algorithm for Modern Mixed-Size Designs
In this paper, we present a new multipacking-tree (MP-tree) representation for macro placements to handle modern mixed-size designs with large macros and high chip utilization rate...
Tung-Chieh Chen, Ping-Hung Yuh, Yao-Wen Chang, Few...