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BMCBI
2008
146views more  BMCBI 2008»
13 years 8 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 3 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BMCBI
2006
169views more  BMCBI 2006»
13 years 8 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
BMCBI
2008
200views more  BMCBI 2008»
13 years 8 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
NAR
2008
74views more  NAR 2008»
13 years 8 months ago
Gene Ontology annotations at SGD: new data sources and annotation methods
The Saccharomyces Genome Database (SGD; http:// www.yeastgenome.org/) collects and organizes biological information about the chromosomal features and gene products of the budding...
Eurie L. Hong, Rama Balakrishnan, Qing Dong, Karen...