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» The Importance of Symmetric Representation
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BMCBI
2007
120views more  BMCBI 2007»
13 years 9 months ago
Phylo-mLogo: an interactive and hierarchical multiple-logo visualization tool for alignment of many sequences
Background: When aligning several hundreds or thousands of sequences, such as epidemic virus sequences or homologous/orthologous sequences of some big gene families, to reconstruc...
Arthur Chun-Chieh Shih, D. T. Lee, Chin-Lin Peng, ...
BMCBI
2010
186views more  BMCBI 2010»
13 years 9 months ago
Knowledge-based biomedical word sense disambiguation: comparison of approaches
Background: Word sense disambiguation (WSD) algorithms attempt to select the proper sense of ambiguous terms in text. Resources like the UMLS provide a reference thesaurus to be u...
Antonio Jimeno Yepes, Alan R. Aronson
BMCBI
2007
112views more  BMCBI 2007»
13 years 9 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2008
136views more  BMCBI 2008»
13 years 9 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...