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BMCBI
2008
87views more  BMCBI 2008»
13 years 7 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2010
121views more  BMCBI 2010»
13 years 7 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
IJON
2006
95views more  IJON 2006»
13 years 7 months ago
Ensemble classifiers based on correlation analysis for DNA microarray classification
Since accurate classification of DNA microarray is a very important issue for the treatment of cancer, it is more desirable to make a decision by combining the results of various ...
Kyung-Joong Kim, Sung-Bae Cho
BMCBI
2007
175views more  BMCBI 2007»
13 years 7 months ago
Fast automated cell phenotype image classification
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...
BMCBI
2011
13 years 2 months ago
Phenotype Recognition with Combined Features and Random Subspace Classifier Ensemble
Background: Automated, image based high-content screening is a fundamental tool for discovery in biological science. Modern robotic fluorescence microscopes are able to capture th...
Bailing Zhang, Tuan D. Pham