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BMCBI
2010
105views more  BMCBI 2010»
13 years 10 months ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
BMCBI
2010
120views more  BMCBI 2010»
13 years 10 months ago
Short clones or long clones? A simulation study on the use of paired reads in metagenomics
Background: Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of met...
Suparna Mitra, Max Schubach, Daniel H. Huson
BMCBI
2007
123views more  BMCBI 2007»
13 years 10 months ago
Tracembler - software for in-silico chromosome walking in unassembled genomes
Background: Whole genome shotgun sequencing produces increasingly higher coverage of a genome with random sequence reads. Progressive whole genome assembly and eventual finishing ...
Qunfeng Dong, Matthew D. Wilkerson, Volker Brendel
BMCBI
2008
102views more  BMCBI 2008»
13 years 10 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes
BMCBI
2008
92views more  BMCBI 2008»
13 years 10 months ago
A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
Samiran Ghosh, David F. Grant, Dipak K. Dey, Denni...