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ICARIS
2010
Springer
13 years 11 months ago
Defining a Simulation Strategy for Cancer Immunocompetence
Although there are various types of cancer treatments, none of these currently take into account the effect of ageing of the immune system and hence altered responses to cancer. R...
Grazziela P. Figueredo, Uwe Aickelin
BMCBI
2010
97views more  BMCBI 2010»
13 years 10 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
BMCBI
2008
126views more  BMCBI 2008»
13 years 10 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
BMCBI
2007
154views more  BMCBI 2007»
13 years 10 months ago
PepBank - a database of peptides based on sequence text mining and public peptide data sources
Background: Peptides are important molecules with diverse biological functions and biomedical uses. To date, there does not exist a single, searchable archive for peptide sequence...
Timur Shtatland, Daniel Guettler, Misha Kossodo, M...
CORR
2010
Springer
116views Education» more  CORR 2010»
13 years 10 months ago
Where are the hard manipulation problems?
One possible escape from the Gibbard-Satterthwaite theorem is computational complexity. For example, it is NP-hard to compute if the STV rule can be manipulated. However, there is...
Toby Walsh