BLASTP is the most popular tool to perform comparative sequence analysis of protein sequences. An exponential increase in the size of protein sequence databases in recent years, h...
Arpith C. Jacob, Joseph M. Lancaster, Jeremy Buhle...
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Biologists currently devote significant time and effort searching information for their research. The wide diversity in terminology used inhibit effective computerized and manual...
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...