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» The PIR-International Protein Sequence Database
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BMCBI
2006
102views more  BMCBI 2006»
13 years 7 months ago
Protein secondary structure prediction for a single-sequence using hidden semi-Markov models
Background: The accuracy of protein secondary structure prediction has been improving steadily towards the 88% estimated theoretical limit. There are two types of prediction algor...
Zafer Aydin, Yucel Altunbasak, Mark Borodovsky
JMLR
2012
11 years 10 months ago
Active Clustering of Biological Sequences
Given a point set S and an unknown metric d on S, we study the problem of efficiently partitioning S into k clusters while querying few distances between the points. In our model...
Konstantin Voevodski, Maria-Florina Balcan, Heiko ...
BMCBI
2007
129views more  BMCBI 2007»
13 years 7 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2006
152views more  BMCBI 2006»
13 years 7 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2006
136views more  BMCBI 2006»
13 years 7 months ago
Java GUI for InterProScan (JIPS): A tool to help process multiple InterProScans and perform ortholog analysis
Background: Recent, rapid growth in the quantity of available genomic data has generated many protein sequences that are not yet biochemically classified. Thus, the prediction of ...
Aijazuddin Syed, Chris Upton