Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
FROST (Fold Recognition-Oriented Search Tool) [6] is a software whose purpose is to assign a 3D structure to a protein sequence. It is based on a series of filters and uses a dat...
Vincent Poirriez, Rumen Andonov, Antoine Marin, Je...
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
A labeled sequence data set related to a certain biological property is often biased and, therefore, does not completely capture its diversity in nature. To reduce this sampling b...