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BMCBI
2002
95views more  BMCBI 2002»
13 years 7 months ago
The functional importance of disease-associated mutation
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Sean D. Mooney, Teri E. Klein
ICDE
2004
IEEE
139views Database» more  ICDE 2004»
14 years 8 months ago
Engineering a Fast Online Persistent Suffix Tree Construction
Online persistent suffix tree construction has been considered impractical due to its excessive I/O costs. However, these prior studies have not taken into account the effects of ...
Srikanta J. Bedathur, Jayant R. Haritsa
BMCBI
2011
12 years 11 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
NAR
2006
75views more  NAR 2006»
13 years 7 months ago
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups
The OrthoMCL database (http://orthomcl.cbil.upenn. edu) houses ortholog group predictions for 55 spe10 cies, including 16 bacterial and 4 archaeal genomes representing phylogeneti...
Feng Chen, Aaron J. Mackey, Christian J. Stoeckert...
ICASSP
2008
IEEE
14 years 1 months ago
Fusion of cleavage site detection and pairwise alignment for fast subcellular localization
In recent years, homology-based and signal-based methods have been proposed for predicting the subcellular localization of proteins. While it has been known that homology-based me...
Man-Wai Mak, Sun-Yuan Kung