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» The Pfam protein families database
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ISMB
1997
13 years 8 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
JCB
2000
107views more  JCB 2000»
13 years 7 months ago
A Discriminative Framework for Detecting Remote Protein Homologies
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
Tommi Jaakkola, Mark Diekhans, David Haussler
NAR
2000
152views more  NAR 2000»
13 years 7 months ago
ASDB: database of alternatively spliced genes
Version 2.1 of ASDB (Alternative Splicing Data Base) contains 1922 protein and 2486 DNA sequences. The protein entries from SWISS-PROT are joined into clusters corresponding to al...
I. Dralyuk, Michael Brudno, Mikhail S. Gelfand, Ma...
BMCBI
2005
99views more  BMCBI 2005»
13 years 7 months ago
Super paramagnetic clustering of protein sequences
Background: Detection of sequence homologues represents a challenging task that is important for the discovery of protein families and the reliable application of automatic annota...
Igor V. Tetko, Axel Facius, Andreas Ruepp, Hans-We...
BMCBI
2006
114views more  BMCBI 2006»
13 years 7 months ago
Taxonomic colouring of phylogenetic trees of protein sequences
Background: Phylogenetic analyses of protein families are used to define the evolutionary relationships between homologous proteins. The interpretation of protein-sequence phyloge...
Gareth Palidwor, Emmanuel G. Reynaud, Miguel A. An...