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» The Power of Comparative Reasoning
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132
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BMCBI
2006
144views more  BMCBI 2006»
15 years 3 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
153
Voted
BMCBI
2006
211views more  BMCBI 2006»
15 years 3 months ago
Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding s
Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
Xian Wang, Ao Li, Zhaohui Jiang, Huanqing Feng
148
Voted
BMCBI
2006
111views more  BMCBI 2006»
15 years 3 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover
147
Voted
BMCBI
2006
125views more  BMCBI 2006»
15 years 3 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
150
Voted
BMCBI
2006
114views more  BMCBI 2006»
15 years 3 months ago
A direct comparison of protein interaction confidence assignment schemes
Background: Recent technological advances have enabled high-throughput measurements of protein-protein interactions in the cell, producing large protein interaction networks for v...
Silpa Suthram, Tomer Shlomi, Eytan Ruppin, Roded S...