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AMC
2007
154views more  AMC 2007»
13 years 8 months ago
A hybrid particle swarm optimization-back-propagation algorithm for feedforward neural network training
The particle swarm optimization algorithm was showed to converge rapidly during the initial stages of a global search, but around global optimum, the search process will become ve...
Jing-Ru Zhang, Jun Zhang, Tat-Ming Lok, Michael R....
BMCBI
2010
95views more  BMCBI 2010»
13 years 8 months ago
Quantifying the relationship between sequence and three-dimensional structure conservation in RNA
Background: In recent years, the number of available RNA structures has rapidly grown reflecting the increased interest on RNA biology. Similarly to the studies carried out two de...
Emidio Capriotti, Marc A. Martí-Renom
BMCBI
2008
130views more  BMCBI 2008»
13 years 8 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2007
157views more  BMCBI 2007»
13 years 8 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...
David B. Burdick, Christopher C. Cavnor, Jeremy Ha...