Sciweavers

1601 search results - page 76 / 321
» The Protein Data Bank
Sort
View
164
Voted
BMCBI
2010
123views more  BMCBI 2010»
14 years 11 months ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
156
Voted
BMCBI
2006
159views more  BMCBI 2006»
15 years 4 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
148
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 1 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
VLDB
2005
ACM
125views Database» more  VLDB 2005»
16 years 4 months ago
Sync your data: update propagation for heterogeneous protein databases
The traditional model of bench (wet) chemistry in many life sciences domain is today actively complimented by computer-based discoveries utilizing the growing number of online data...
Kajal T. Claypool, Elke A. Rundensteiner
RECOMB
2005
Springer
16 years 4 months ago
Efficient Algorithms for Detecting Signaling Pathways in Protein Interaction Networks
Abstract. The interpretation of large-scale protein network data depends on our ability to identify significant sub-structures in the data, a computationally intensive task. Here w...
Jacob Scott, Trey Ideker, Richard M. Karp, Roded S...