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ALMOB
2008
82views more  ALMOB 2008»
13 years 7 months ago
Protein sequence and structure alignments within one framework
Background: Protein structure alignments are usually based on very different techniques to sequence alignments. We propose a method which treats sequence, structure and even combi...
Gundolf Schenk, Thomas Margraf, Andrew E. Torda
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
13 years 7 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
BMCBI
2007
121views more  BMCBI 2007»
13 years 7 months ago
A procedure for identifying homologous alternative splicing events
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...
David Talavera, Adam Hospital, Modesto Orozco, Xav...
CORR
2010
Springer
249views Education» more  CORR 2010»
13 years 7 months ago
Lower Bounds on Near Neighbor Search via Metric Expansion
In this paper we show how the complexity of performing nearest neighbor (NNS) search on a metric space is related to the expansion of the metric space. Given a metric space we loo...
Rina Panigrahy, Kunal Talwar, Udi Wieder
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu