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148
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BMCBI
2010
15 years 4 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
129
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GPEM
2008
15 years 4 months ago
2008
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
136
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BMCBI
2006
15 years 4 months ago
2006
Background: Defensins are antimicrobial peptides of innate immunity functioning by non-specific binding to anionic phospholipids in bacterial membranes. Their cationicity, amphipa...
121
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BMCBI
2006
15 years 4 months ago
2006
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
147
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BMCBI
2006
15 years 4 months ago
2006
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...