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    BMCBI
    2007
    115views more  BMCBI 2007»
    Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
    13 years 8 months ago
    Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
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    Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
    Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
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    BMCBI
    2007
    144views more  BMCBI 2007»
    Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
    13 years 8 months ago
    Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
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    Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
    Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
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    BMCBI
    2007
    116views more  BMCBI 2007»
    Clustering protein environments for function prediction: finding PROSITE motifs in 3D
    13 years 8 months ago
    Clustering protein environments for function prediction: finding PROSITE motifs in 3D
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    Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
    Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
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    BMCBI
    2007
    154views more  BMCBI 2007»
    Inferring biological networks with output kernel trees
    13 years 8 months ago
    Inferring biological networks with output kernel trees
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    Background: Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Computational approaches to this problem ...
    Pierre Geurts, Nizar Touleimat, Marie Dutreix, Flo...
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    BMCBI
    2007
    136views more  BMCBI 2007»
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
    13 years 8 months ago
    Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
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    Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
    Xiaoyu Chen, Mathieu Blanchette
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