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» The Transformational Approach to Program Development
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BMCBI
2005
142views more  BMCBI 2005»
13 years 8 months ago
CLU: A new algorithm for EST clustering
Background: The continuous flow of EST data remains one of the richest sources for discoveries in modern biology. The first step in EST data mining is usually associated with EST ...
Andrey A. Ptitsyn, Winston Hide
SIGCSE
2002
ACM
118views Education» more  SIGCSE 2002»
13 years 7 months ago
A proposed undergraduate bioinformatics curriculum for computer scientists
Bioinformatics is a new and rapidly evolving discipline that has emerged from the fields of experimental molecular biology and biochemistry, and from the the artificial intelligen...
Travis E. Doom, Michael L. Raymer, Dan E. Krane, O...
VLDB
2002
ACM
151views Database» more  VLDB 2002»
13 years 7 months ago
Preference SQL - Design, Implementation, Experiences
Current search engines can hardly cope adequately with fuzzy predicates defined by complex preferences. The biggest problem of search engines implemented with standard SQL is that...
Werner Kießling, Gerhard Köstler
INFORMS
2010
145views more  INFORMS 2010»
13 years 6 months ago
An Automated Intensity-Modulated Radiation Therapy Planning System
We design and implement an intensity-modulated radiation therapy (IMRT) plan generation technology that effectively and efficiently optimizes beam geometry as well as beam intens...
Shabbir Ahmed, Ozan Gozbasi, Martin W. P. Savelsbe...
MP
2010
135views more  MP 2010»
13 years 6 months ago
An inexact Newton method for nonconvex equality constrained optimization
Abstract We present a matrix-free line search algorithm for large-scale equality constrained optimization that allows for inexact step computations. For sufficiently convex problem...
Richard H. Byrd, Frank E. Curtis, Jorge Nocedal