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GCB
2005
Springer
138views Biometrics» more  GCB 2005»
15 years 11 months ago
Inferring Regulatory Systems with Noisy Pathway Information
: With increasing number of pathways available in public databases, the process of inferring gene regulatory networks becomes more and more feasible. The major problem of most of t...
Christian Spieth, Felix Streichert, Nora Speer, An...
GECCO
2004
Springer
117views Optimization» more  GECCO 2004»
15 years 11 months ago
Bistability of the Needle Function in the Presence of Truncation Selection
It is possible for a GA to have two stable fixed points on a single-peak fitness landscape. These can correspond to meta-stable finite populations. This phenomenon is called bis...
Alden H. Wright, Greg Cripe
IJCAI
2007
15 years 7 months ago
Integration of Hybrid Bio-Ontologies using Bayesian Networks for Knowledge Discovery
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
Kenneth McGarry, Sheila Garfield, Nick Morris, Ste...
IJBRA
2006
59views more  IJBRA 2006»
15 years 6 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey