There is an increasing need to automatically annotate a set of genes or proteins (from genome sequencing, DNA microarray analysis or protein 2D gel experiments) using controlled v...
Jianmin Wu, Xizeng Mao, Tao Cai, Jingchu Luo, Lipi...
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Background: One of the essential processing events during pre-mRNA maturation is the posttranscriptional addition of a polyadenine [poly(A)] tail. The 3'-end poly(A) track pr...
Guoli Ji, Jianti Zheng, Yingjia Shen, Xiaohui Wu, ...