Background: Some of the recent investigations in systems biology have revealed the existence of a complex regulatory network between genes, microRNAs (miRNAs) and transcription fa...
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
Kuo Ping Chiu, Chee-Hong Wong, Qiongyu Chen, Prami...
Background: A fundamental goal of the U.S. National Institute of Health (NIH) "Roadmap" is to strengthen Translational Research, defined as the movement of discoveries i...
Alan Ruttenberg, Tim Clark, William Bug, Matthias ...
Background: Microarray-based measurement of mRNA abundance assumes a linear relationship between the fluorescence intensity and the dye concentration. In reality, however, the cal...
Leming M. Shi, Weida Tong, Zhenqiang Su, Tao Han, ...