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BMCBI
2007
121views more  BMCBI 2007»
13 years 8 months ago
A constrained polynomial regression procedure for estimating the local False Discovery Rate
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...
Cyril Dalmasso, Avner Bar-Hen, Philippe Broët
BMCBI
2007
109views more  BMCBI 2007»
13 years 8 months ago
A cis-regulatory logic simulator
Background: A major goal of computational studies of gene regulation is to accurately predict the expression of genes based on the cis-regulatory content of their promoters. The d...
Robert D. Zeigler, Jason Gertz, Barak A. Cohen
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
Quantitative analysis of numerical solvers for oscillatory biomolecular system models
Background: This article provides guidelines for selecting optimal numerical solvers for biomolecular system models. Because various parameters of the same system could have drast...
Chang F. Quo, May D. Wang
APIN
2006
168views more  APIN 2006»
13 years 8 months ago
Utilizing Genetic Algorithms to Optimize Membership Functions for Fuzzy Weighted Association Rules Mining
It is not an easy task to know a priori the most appropriate fuzzy sets that cover the domains of quantitative attributes for fuzzy association rules mining. In general, it is unre...
Mehmet Kaya, Reda Alhajj