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» The Virtual Gene Genetic Algorithm
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BMCBI
2007
111views more  BMCBI 2007»
13 years 11 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2011
13 years 2 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
WOB
2004
134views Bioinformatics» more  WOB 2004»
14 years 11 days ago
Reconstruction of Phylogenetic Trees using the Ant Colony Optimization Paradigm
We developed a new approach for the reconstruction of phylogenetic trees using ant colony optimization metaheuristics.Atree is constructed using a fully connected graph and the pro...
Heitor S. Lopes, Mauricio Perretto
BMCBI
2011
13 years 2 months ago
MINE: Module Identification in NEtworks
Background: Graphical models of network associations are useful for both visualizing and integrating multiple types of association data. Identifying modules, or groups of function...
Kahn Rhrissorrakrai, Kristin C. Gunsalus
BMCBI
2007
95views more  BMCBI 2007»
13 years 11 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim