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BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
Lucy Skrabanek, Marta Murcia, Michel Bouvier, Laks...
IMSCCS
2007
IEEE
14 years 1 months ago
Evolutionary Conservation of DNA-Contact residues in DNA-binding Domains
Background: DNA-binding proteins are of utmost importance to gene regulation. The identification of DNA-binding domains is useful for understanding the regulation mechanisms of DN...
Yao-Lin Chang, Huai-Kuang Tsai, Cheng-Yan Kao, Yun...
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
IMSCCS
2007
IEEE
14 years 1 months ago
Asymmetric Bagging and Feature Selection for Activities Prediction of Drug Molecules
Background: Activities of drug molecules can be predicted by QSAR (quantitative structure activity relationship) models, which overcomes the disadvantages of high cost and long cy...
Guo-Zheng Li, Hao-Hua Meng, Mary Qu Yang, Jack Y. ...
CASCON
1992
127views Education» more  CASCON 1992»
13 years 8 months ago
Overview of multidatabase transaction management
A multidatabase system (MDBS) is a facility that allows users access to data located in multiple autonomous database management systems (DBMSs). In such a system, globaltransaction...
Yuri Breitbart, Hector Garcia-Molina, Abraham Silb...