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BMCBI
2004
112views more  BMCBI 2004»
13 years 7 months ago
SPOC: A widely distributed domain associated with cancer, apoptosis and transcription
Background: The Split ends (Spen) family are large proteins characterised by N-terminal RNA recognition motifs (RRMs) and a conserved SPOC (Spen paralog and ortholog C-terminal) d...
Luis Sánchez-Pulido, Ana María Rojas...
BMCBI
2011
12 years 11 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BMCBI
2011
13 years 2 months ago
Estimating developmental states of tumors and normal tissues using a linear time-ordered model
Background: Tumor cells are considered to have an aberrant cell state, and some evidence indicates different development states appearing in the tumorigenesis. Embryonic developme...
Bo Zhang, Beibei Chen, Tao Wu, Zhenyu Xuan, Xiaope...
IPMI
2005
Springer
14 years 1 months ago
Imaging Tumor Microenvironment with Ultrasound
Abstract. Recent advances in molecular biology are providing new opportunities for breast cancer imaging. Our approach uses ultrasound to image viscoelastic features of tumors. The...
Mallika Sridhar, Michael F. Insana
CMPB
2010
109views more  CMPB 2010»
13 years 7 months ago
Cell Accelerated Cryoablation Simulation
Abstract. Tracking growth of lethal ice is critical to success of percutaneous ablations using supercooled probes introduced into cancerous lesions. Physicians lack planning tools ...
Daniel J. Blezek, David G. Carlson, Lionel T. Chen...