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BMCBI
2010
131views more  BMCBI 2010»
13 years 7 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
CSDA
2006
81views more  CSDA 2006»
13 years 7 months ago
Flexible temporal expression profile modelling using the Gaussian process
Time course gene expression experiments have proved valuable in a variety of biological studies [e.g., Chuang, Y., Chen, Y., Gadisetti, V., et al., 2002. Gene expression after tre...
Ming Yuan
BMCBI
2007
157views more  BMCBI 2007»
13 years 7 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
CORR
2010
Springer
111views Education» more  CORR 2010»
13 years 4 months ago
Analysis Of Cancer Omics Data In A Semantic Web Framework
Our work concerns the elucidation of the cancer (epi)genome, transcriptome and proteome to better understand the complex interplay between a cancer cell's molecular state and ...
Matthew Holford, James P. McCusker, Kei-Hoi Cheung...
BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang