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BMCBI
2006
171views more  BMCBI 2006»
13 years 7 months ago
The Autoimmune Disease Database: a dynamically compiled literature-derived database
Background: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically dist...
Thomas Karopka, Juliane Fluck, Heinz-Theodor Mevis...
BMCBI
2006
178views more  BMCBI 2006»
13 years 7 months ago
GOLEM: an interactive graph-based gene-ontology navigation and analysis tool
Background: The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for na...
Rachel S. G. Sealfon, Matthew A. Hibbs, Curtis Hut...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2007
167views more  BMCBI 2007»
13 years 7 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk
BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Evaluation of high-throughput functional categorization of human disease genes
Background: Biological data that are well-organized by an ontology, such as Gene Ontology, enables high-throughput availability of the semantic web. It can also be used to facilit...
James L. Chen, Yang Liu, Lee T. Sam, Jianrong Li, ...