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    BMCBI
    2008
    128views more  BMCBI 2008»
    Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
    13 years 8 months ago
    Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
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    Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
    Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
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    BMCBI
    2010
    174views more  BMCBI 2010»
    The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
    13 years 8 months ago
    The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
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    Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
    Junbai Wang
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    BMCBI
    2007
    156views more  BMCBI 2007»
    Large-scale clustering of CAGE tag expression data
    13 years 8 months ago
    Large-scale clustering of CAGE tag expression data
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    Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
    Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
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    BMCBI
    2010
    151views more  BMCBI 2010»
    Using diffusion distances for flexible molecular shape comparison
    13 years 8 months ago
    Using diffusion distances for flexible molecular shape comparison
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    Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
    Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
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    BMCBI
    2007
    129views more  BMCBI 2007»
    Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping
    13 years 8 months ago
    Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping
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    Background: The Sulston score is a well-established, though approximate metric for probabilistically evaluating postulated clone overlaps in DNA fingerprint mapping. It is known t...
    Michael C. Wendl
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