Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
The informative value of biomolecular networks has shifted from being solely information resources for possible cellular partners (whether these embody proteins, (ribo)nucleic aci...
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...