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BMCBI
2010
138views more  BMCBI 2010»
13 years 11 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
BMCBI
2007
147views more  BMCBI 2007»
13 years 11 months ago
Hon-yaku: a biology-driven Bayesian methodology for identifying translation initiation sites in prokaryotes
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
Yuko Makita, Michiel J. L. de Hoon, Antoine Danchi...
BMCBI
2006
96views more  BMCBI 2006»
13 years 11 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
BMCBI
2007
149views more  BMCBI 2007»
13 years 10 months ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...
BMCBI
2005
119views more  BMCBI 2005»
13 years 10 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona