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» The existence of k-radius sequences
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BMCBI
2007
89views more  BMCBI 2007»
13 years 10 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2005
132views more  BMCBI 2005»
13 years 10 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
BMCBI
2004
94views more  BMCBI 2004»
13 years 10 months ago
GASP: Gapped Ancestral Sequence Prediction for proteins
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
Richard J. Edwards, Denis C. Shields
BMCBI
2004
102views more  BMCBI 2004»
13 years 10 months ago
FRAGS: estimation of coding sequence substitution rates from fragmentary data
Background: Rates of substitution in protein-coding sequences can provide important insights into evolutionary processes that are of biomedical and theoretical interest. Increased...
Estienne C. Swart, Winston A. Hide, Cathal Seoighe
PVLDB
2008
107views more  PVLDB 2008»
13 years 9 months ago
Finding relevant patterns in bursty sequences
Sequence data is ubiquitous and finding frequent sequences in a large database is one of the most common problems when analyzing sequence data. Unfortunately many sources of seque...
Alexander Lachmann, Mirek Riedewald